Linked Life Data

540255

Source:http://linkedlifedata.com/resource/pubmed/id/540255

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1980-6-16
pubmed:abstractText
Cells of Halobacterium cutirubrum were grown in the presence of [14C]mevalonate with and without 3 mM nicotine. Growth of cells was inhibited to a maximum extent of 25% but overall incorporation of 14C into total, neutral, or polar lipids was only inhibited about 16% during active growth and to a much lesser extent or not at all in stationary phase. Little effect of nicotine on labelling of squalenes, vitamin MK-8, geranylgeraniol, and phytoene was observed. However, labelling of bacterioruberin and monoanhydrobacterioruberin was extensively inhibited while that of lycopene and bisanhydrobacterioruberin was increased reciprocally by growth in the presence of 3 mM nicotine. Reincubation of the labelled nicotine-grown cells in fresh cold medium without nicotine restored the 14C-labelling of bacterioruberin and monoanhydrobacterioruberin at the expense of lycopene and bisanhydrobacterioruberin. These results confirm our previous findings suggesting that the C50 bacterioruberin is made by addition of a C5-isoprene unit to each end of the C40-lycopene chain, followed by introduction of four hydroxyl groups.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0008-4166
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1292-7
pubmed:dateRevised
2001-11-2
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Studies of the biosynthesis of C50 carotenoids in Halobacterium cutirubrum.
pubmed:publicationType
Journal Article