Linked Life Data

537251

Source:http://linkedlifedata.com/resource/pubmed/id/537251

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-5-23
pubmed:abstractText
Effects of surugatoxin (SGTX), a new ganglionic blocking agent on adrenergically innervated tissues: guinea pig isolated atria and vas deferens were investigated. SGTX (1, 10 muM) markedly reduced the cardiostimulatory response of the atria to nicotine and also partially the response to 1,1-dimethyl-4-phenylpiperazinium (DMPP) and 5-hydroxytryptamine, without affecting responses to noradrenaline, tyramine and histamine. The contractile response of the vas deferens to nicotine, DMPP and hypogastric nerve stimulation was markedly reduced by SGTX (1, 10 muM), whereas that to noradrenaline, acetylcholine and transmural stimulation was not affected. These results indicate that SGTX has an antagonistic action on nicotinic receptors in these tissues as well as in sympathetic ganglia and in guinea pig ileum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0021-5198
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
295-302
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Effects of surugatoxin on adrenergically innervated tissues.
pubmed:publicationType
Journal Article, In Vitro