Linked Life Data

4073291

Source:http://linkedlifedata.com/resource/pubmed/id/4073291

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6 Pt 2
pubmed:dateCreated
1986-1-23
pubmed:abstractText
Flights across time zones produce an abrupt displacement of the environmental time cues (zeitgebers), and the endogenous circadian timing system resynchronizes only gradually to the new schedule. A coupled two-oscillator model can simulate the human circadian system in temporal isolation and in artificial zeitgeber cycles. The model is here shown to explain the major features of resynchronization of circadian rhythms after time zone shifts, i.e., the rate of adjustment depends on the rhythm being measured, the number of time zones crossed, the flight direction (eastward or westward), and the strength of the zeitgebers in the new time zone. Investigations of the contribution of different model parameters to system performances suggest that intersubject differences in pacemaker periods may be a major factor in the observed variability in the effects of time zone shifts on circadian rhythms. With individualized period estimate the models can simulate case studies in which four subjects recorded their sleep-wake and core body temperature rhythms throughout simple and complex patterns of transmeridian flights.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
249
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
R704-19
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Phase shifting two coupled circadian pacemakers: implications for jet lag.
pubmed:publicationType
Journal Article