Linked Life Data

4052299

Source:http://linkedlifedata.com/resource/pubmed/id/4052299

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1985-12-20
pubmed:abstractText
In a previous study of the potential mutagenic action of isoflurane using the sister chromatid exchange (SCE) test in lymphocytes of surgical patients, it appeared that SCE increased in a group of 11 cigarette smokers, there being no effect in patients who were non-smokers. In the present study, 63 cigarette smokers were examined by the SCE test before and after minor orthopaedic operations undertaken under halothane or isoflurane anaesthesia, or subarachnoid analgesia. No significant changes of SCE were observed, and the risk of having missed a "true" increase of more than 0.6 SCE per cell was less than 1%. It was concluded that, in cigarette smokers, SCE in lymphocytes were unchanged after both general anaesthesia and subarachnoid analgesia, and that there was no indication from the SCE test of a mutagenic action of halothane, or isofurane, in nitrous oxide.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0007-0912
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1100-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Sister chromatid exchanges in cigarette smokers: effects of halothane, isoflurane or subarachnoid blockade.
pubmed:publicationType
Journal Article