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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1986-4-7
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pubmed:abstractText |
Cancerous tissue from 86 patients with primary gastric cancer were examined for the presence of receptors for estrogen (ER) and progesterone (PgR). ER and PgR were present in 8 (15.4%) and 5 (9.6%), respectively, of 52 male patients, 9 (26.6%) and 7 (20.6%), respectively, of 34 female patients, a total of 17 (19.8%) and 12 (14.0%), respectively. One male patient (1.9%) and 4 female patients (11.8%) had both ER and PgR, and 40 male (76.9%) and 22 female patients (64.7%) showed no ER or PgR. The binding activity ranged from 6 to 200 fmol/mg protein for estradiol and from 5 to 58 fmol/mg protein for progesterone. ER- and/or PgR-positive cases were characterized grossly as Borrmann type 4, and microscopically as diffuse type with scirrhous growth pattern. The presence of ER and/or PgR in some gastric cancers indicates the possibility that sex hormonal factors are involved in these tumors.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1376-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3948119-Adult,
pubmed-meshheading:3948119-Aged,
pubmed-meshheading:3948119-Female,
pubmed-meshheading:3948119-Gonadal Steroid Hormones,
pubmed-meshheading:3948119-Humans,
pubmed-meshheading:3948119-Male,
pubmed-meshheading:3948119-Middle Aged,
pubmed-meshheading:3948119-Promegestone,
pubmed-meshheading:3948119-Receptors, Estrogen,
pubmed-meshheading:3948119-Receptors, Progesterone,
pubmed-meshheading:3948119-Stomach Neoplasms
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pubmed:year |
1986
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pubmed:articleTitle |
Estrogen and progesterone receptors in gastric cancer.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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