Linked Life Data

394583

Source:http://linkedlifedata.com/resource/pubmed/id/394583

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1980-4-25
pubmed:abstractText
The author used the scanning electron microscope (SEM) to study the influence of urokinase on subarachnoid fibrosis after experimental subarachnoid haemorrhage (SAH). In the subchronic group of dogs, which were sacrificed three weeks after SAH, an average of 45--50 IU/kg of intrathecal urokinase diminished the fibrosis. In the chronic group, which was sacrificed three months after SAH, an average of 250 IU/kg of intrathecal urokinase also had considerable reducing effect. The author supposes that fibrinolytic therapy, with lysis of blood clot, contributes to clearance of the blood. We contrast this mechanism with the mechanism and effect of antifibrinolytic therapy. This experiment is the first successful attempt to influence subarachnoid fibrosis, and also the first experiment in which subarachnoid fibrosis could to some extent be prevented.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-6268
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
51-63
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Prevention of subarachnoid fibrosis after subarachnoid haemorrhage with urokinase. Scanning electron microscopic study in the dog.
pubmed:publicationType
Journal Article