Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-10-22
pubmed:abstractText
Fluorescent antinuclear antibody (ANA) testing was performed on 141 sera from 114 patients with well defined rheumatic diseases including fibrositis syndrome and 24 sera from 24 healthy subjects using HEp-2 cells and rat liver as substrates. ANA titers were almost always higher on HEp-2, in most cases by 1:5 dilutions. ANA positivity or negativity was usually substrate independent, but there were exceptions. Two patients with SLE were ANA positive on HEp-2 only and rat liver only, respectively; patterns were homogeneous. Thirteen of 15 CREST patients had anticentromere antibodies, detected on HEp-2 only. "False-positive" ANA were invariably low titer, speckled and confined to one substrate.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0315-162X
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
265-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Clinical comparison of cultured human epithelial cells and rat liver as substrates for the fluorescent antinuclear antibody test.
pubmed:publicationType
Journal Article, Comparative Study