Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1985-11-25
pubmed:abstractText
Nine patients with chronic glomerulonephritis were investigated in a controlled, double-blind, crossover study to assess the efficacy of prostaglandin E1 (PGE1) infusion therapy. Three-hour intravenous infusions of PGE1 (100 micrograms/day) and placebo were performed every day for three weeks, respectively. Improvement of renal function was demonstrated by statistical u-test (p less than 0.01) and x2-test (p less than 0.05). Three weeks infusion of PGE1 tended to increase creatinine clearance. PGE1 infusion significantly decreased the serum level of creatinine as compared with the placebo infusion (p less than 0.05). The urinary excretion of protein, however, did not change with PGE1. It was concluded that PGE1 infusion is effective in improving renal function in patients with chronic glomerulonephritis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0262-1746
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
227-33
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Prostaglandin E1 infusion therapy in chronic glomerulonephritis--a double-blind, crossover trial.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Controlled Clinical Trial