Linked Life Data

3794673

Source:http://linkedlifedata.com/resource/pubmed/id/3794673

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1987-2-12
pubmed:abstractText
In order to elucidate the mechanisms of breast-feeding-induced resistance to respiratory syncytial virus (RSV) infection, groups of breast-fed and bottle-fed infants with this infection were tested at the onset of illness and then again 1 and 2 weeks later for the presence of interferon (IFN) as well as of virus-specific lymphocyte transformation (LTF) activity. Alpha-IFN was detected in nine out of ten breast-fed infants, while it was found in only 11 out of 21 bottle-fed subjects. The rate of the detection of IFN was significantly higher in the former group (P less than .05). Mean levels of IFN activity were also higher in breast-fed infants than in bottle-fed subjects during the course of the illness. It was noted, however, that previous breast feeding elicited little enhancing effect on the IFN response of infants with RSV infection. Combining the two feeding groups, suppressed LTF activity to RSV seemed to be related to a positive IFN response, although the association was not statistically significant. These observations suggest that breast feeding has unique mechanisms for modulating the immune response of infants with RSV infection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0146-6615
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7-14
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Effect of breast feeding on responses of systemic interferon and virus-specific lymphocyte transformation in infants with respiratory syncytial virus infection.
pubmed:publicationType
Journal Article, Comparative Study