Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4 Pt 2
|
pubmed:dateCreated |
1986-8-14
|
pubmed:abstractText |
Hematoporphyrin derivative has an affinity for malignant tissue and emits a red fluorescence when exposed to excitatory light. Therefore it is theoretically possible to make a diagnosis of cancer localization by observation of this fluorescence. The authors have been developing a new imaging system for cancer diagnosis using an excimer-dye laser. The excimer pulse has a 308 nm ultraviolet beam emitted by XeCl. Simplification and accuracy of the fluorescence diagnostic procedure was achieved by utilizing the nature of the pulse and a polychrometer. The diagnostic system permits endoscopic examination under ordinary observation light. Investigations have been performed in animal tumor models including FM-mouse (breast cancer) and beagle dog (esophageal cancer). Tumor tissue showed a distinct fluorescence, but no fluorescence could be observed in normal tissue, 72 hours after hematoporphyrin derivative administration.
|
pubmed:language |
jpn
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0385-0684
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
13
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
|
pubmed:pagination |
1647-52
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3729472-Animals,
pubmed-meshheading:3729472-Dogs,
pubmed-meshheading:3729472-Esophageal Neoplasms,
pubmed-meshheading:3729472-Hematoporphyrins,
pubmed-meshheading:3729472-Lasers,
pubmed-meshheading:3729472-Mammary Neoplasms, Experimental,
pubmed-meshheading:3729472-Mice,
pubmed-meshheading:3729472-Mice, Inbred Strains,
pubmed-meshheading:3729472-Neoplasms, Experimental,
pubmed-meshheading:3729472-Xenon
|
pubmed:year |
1986
|
pubmed:articleTitle |
[A diagnostic imaging system for cancer localization using an excimer dye laser].
|
pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
|