Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4 Pt 2
pubmed:dateCreated
1986-8-14
pubmed:abstractText
Hematoporphyrin derivative has an affinity for malignant tissue and emits a red fluorescence when exposed to excitatory light. Therefore it is theoretically possible to make a diagnosis of cancer localization by observation of this fluorescence. The authors have been developing a new imaging system for cancer diagnosis using an excimer-dye laser. The excimer pulse has a 308 nm ultraviolet beam emitted by XeCl. Simplification and accuracy of the fluorescence diagnostic procedure was achieved by utilizing the nature of the pulse and a polychrometer. The diagnostic system permits endoscopic examination under ordinary observation light. Investigations have been performed in animal tumor models including FM-mouse (breast cancer) and beagle dog (esophageal cancer). Tumor tissue showed a distinct fluorescence, but no fluorescence could be observed in normal tissue, 72 hours after hematoporphyrin derivative administration.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0385-0684
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
N
pubmed:pagination
1647-52
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
[A diagnostic imaging system for cancer localization using an excimer dye laser].
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't