Linked Life Data

3661166

Source:http://linkedlifedata.com/resource/pubmed/id/3661166

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1987-11-3
pubmed:abstractText
This study explored the effect of peripheral and central target tissues on the survival and differentiation of murine statoacoustic ganglion neurons. Isolated ganglia, ganglia with otic sensory epithelia, ganglia with rhombencephalic tissue and ganglia with both otic sensory epithelia and rhombencephalic tissues were explanted from 12.5 gestation-day mouse embryos. All explants developed for 14 days in vitro on the surface of HEMA hydrogel substrata. There were significantly fewer differentiated statoacoustic ganglion neurons in isolated ganglion explants (18.5%) than in explants of ganglia with peripheral (97.2%) or central (87.5%) target tissues or in those explants that contained both targets (93.1%). Our results confirm in the developing mouse that both peripheral and central target tissues exert a trophic influence on the survival and cytodifferentiation of statoacoustic ganglion neurons.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0001-6489
pubmed:author
pubmed:issnType
Print
pubmed:volume
104
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
90-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
The effect of target tissues on survival and differentiation of mammalian statoacoustic ganglion neurons in organ culture.
pubmed:affiliation
Department of Otolaryngology, Hai Guang Hospital, Chinese Academy of Medical Sciences, People's Republic of China.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't