|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
1987-8-19
|
|
pubmed:abstractText |
The strong tumor-selective cytocidal action of tumor necrosis factor (TNF) has been observed in vitro and in vivo. Sato et al. have reported that it was possible to induce a primed state of TNF triggering by injection of purified protein derivative (PPD) even a long time after BCG sensitization, suggesting that this treatment could be applied to human patients. In the present study, we achieved a partial response of a metastatic lesion in a patient with renal cancer by the induction of endogenous TNF by PPD and OK-432 (a streptococcal preparation). This study suggested the possible application of this therapy to also patients with malignant tumor which are highly resistant to any conventional antitumor therapy.
|
|
pubmed:language |
jpn
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0385-0684
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2378-80
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:3606157-Biological Agents,
pubmed-meshheading:3606157-Carcinoma, Renal Cell,
pubmed-meshheading:3606157-Glycoproteins,
pubmed-meshheading:3606157-Humans,
pubmed-meshheading:3606157-Kidney Neoplasms,
pubmed-meshheading:3606157-Lung Neoplasms,
pubmed-meshheading:3606157-Male,
pubmed-meshheading:3606157-Middle Aged,
pubmed-meshheading:3606157-Picibanil,
pubmed-meshheading:3606157-Tuberculin,
pubmed-meshheading:3606157-Tumor Necrosis Factor-alpha
|
|
pubmed:year |
1987
|
|
pubmed:articleTitle |
[Partial response of lung metastases from a renal cancer treated with endogenous tumor necrosis factor].
|
|
pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|
