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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
|
pubmed:dateCreated |
1987-6-19
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pubmed:abstractText |
The segregation of rat esterases controlled by loci residing in linkage group V (LGV) has been studied in two backcross series, (LEW/Han X BN/Han)F1 X LEW/Han and (LEW/Han X LE/Han)F1 X LEW/Han. Es-14 (formerly Es-Si) was shown to be closely linked to Es-1. A new esterase locus, Es-15, was described which codes for a liver isozyme. The distribution pattern of three alleles at the Es-15 locus is presented for 52 independent inbred strains. Close linkage of Es-15 to Es-14 and to Es-1 was established, proposing the following gene order: [Es-2, Es-10]-[ES-1, ES-14, ES-15]. The esterase loci on LGV are thus separated into two gene clusters, cluster 1 and cluster 2. These conclusions are supported by the strain distribution patterns of the two RI strain series, LXB and DXE.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0006-2928
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
79-93
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading | |
pubmed:year |
1987
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pubmed:articleTitle |
Biochemical genetics of Es-14 (formerly Es-Si) and a new esterase variation, Es-15, of the laboratory rat (Rattus norvegicus): biochemistry, tissue expression, and linkage to Es-1 in linkage group V.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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