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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1987-5-1
|
| pubmed:abstractText |
Progesterone-receptor binding affinity of some nonsteroidal molecules was assessed by competitive protein binding assay in rabbit as well as human uterine cytosol in vitro. Of 40 compounds belonging to 5 different series tested, 3-(p-anisoyl)-2-chloro-6, 7-dimethoxy-quinoline exhibited around 50% inhibition whereas 2-(p-anisoyl) naphthalene and 3-substituted phenyl-1-(3-(2-chloro-6, 7-dialkoxy) quinolinyl)prop-2-en-1-one showed around 20% inhibition in 3H-progesterone binding for rabbit and human uterine progesterone receptor.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0232-7384
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
88
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
185-92
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3556407-Animals,
pubmed-meshheading:3556407-Binding, Competitive,
pubmed-meshheading:3556407-Chalcone,
pubmed-meshheading:3556407-Cytosol,
pubmed-meshheading:3556407-Female,
pubmed-meshheading:3556407-Heterocyclic Compounds,
pubmed-meshheading:3556407-Humans,
pubmed-meshheading:3556407-Ketones,
pubmed-meshheading:3556407-Rabbits,
pubmed-meshheading:3556407-Receptors, Progesterone,
pubmed-meshheading:3556407-Uterus
|
| pubmed:year |
1986
|
| pubmed:articleTitle |
Molecular interaction of nonsteroidal compounds with uterine progesterone receptor (Part I).
|
| pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|