rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1987-2-2
|
pubmed:abstractText |
Prostacyclin (PGI2) synthesis in vascular tissue is stimulated by free Ca2+. Concentrations in excess of 4 mM result in a sustained release of PGI2, but not other prostanoids, from rat aorta. This effect arises by increased synthesis of PGI2 and not through the inhibition of its metabolism. Physico-chemical examination of serum and plasma extract has indicated that much of the PGI2-stimulating activity reported for human serum derives from the presence of free Ca2+.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0264-6021
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
239
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
237-9
|
pubmed:dateRevised |
2009-11-18
|
pubmed:meshHeading |
pubmed-meshheading:3541921-Animals,
pubmed-meshheading:3541921-Aorta,
pubmed-meshheading:3541921-Blood,
pubmed-meshheading:3541921-Blood Vessels,
pubmed-meshheading:3541921-Calcium,
pubmed-meshheading:3541921-Chromatography, Gel,
pubmed-meshheading:3541921-Epoprostenol,
pubmed-meshheading:3541921-Hydrogen-Ion Concentration,
pubmed-meshheading:3541921-Prostaglandins,
pubmed-meshheading:3541921-Rats
|
pubmed:year |
1986
|
pubmed:articleTitle |
Prostacyclin synthesis by vascular tissue. Effect of extracellular Ca2+.
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|