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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1986-7-1
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pubmed:abstractText |
A variety of solubilised tissue extracts from cigarette smokers and non-smokers have been screened quantitatively for both placental alkaline phosphatase (PLAP) and placental-like alkaline phosphatase (PLAP-like AP) in order to identify the possible tissue origins of the circulating PLAP-like AP found in most smokers. Lung alveolar tissue, and to a lesser extent colonic tissues, contained both PLAP-like AP and PLAP. Tissues from smokers and non-smokers contained comparable proportions and amounts of PLAP and PLAP-like AP. No other tissue source of PLAP-like AP was found other than those previously reported for testicular, endometrial and thymic tissue. Selective release of PLAP-like AP from the lung in cigarette smokers seems likely to be a major source for this isoenzyme in peripheral circulation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alkaline Phosphatase,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/GPI-Linked Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/alkaline phosphatase, placental
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0009-8981
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
28
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pubmed:volume |
155
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
329-33
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:3519002-Alkaline Phosphatase,
pubmed-meshheading:3519002-Antibodies, Monoclonal,
pubmed-meshheading:3519002-Colon,
pubmed-meshheading:3519002-GPI-Linked Proteins,
pubmed-meshheading:3519002-Humans,
pubmed-meshheading:3519002-Immunoenzyme Techniques,
pubmed-meshheading:3519002-Isoenzymes,
pubmed-meshheading:3519002-Pulmonary Alveoli,
pubmed-meshheading:3519002-Smoking
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pubmed:year |
1986
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pubmed:articleTitle |
Tissue origin of serum placental-like alkaline phosphatase in cigarette smokers.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|