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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1986-6-6
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pubmed:abstractText |
A highly reproducible paired immunofluorescence staining method was used to map the relative distribution of IgA1- and IgA2-producing cells in peripheral lymphoid organs and various secretory tissues. Spleen, peripheral lymph nodes, and tonsils all contained a marked predominance (91 to 95%) of IgA1 immunocytes. However, striking variations were demonstrated among the secretory tissues with regard to the median proportion of IgA1-producing cells: nasal mucosa, 96%; lacrimal glands, 81%; major salivary glands, 66%; mammary glands, 63%; gastric and proximal small intestinal mucosa, 84 to 77%; ileum, 55%; and large bowel, 41%. Thus, IgA2 production is relatively enhanced mainly in the distal gut and in mammary and salivary glands, in that order.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0022-1767
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
136
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3631-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3517160-Animals,
pubmed-meshheading:3517160-Antibodies, Monoclonal,
pubmed-meshheading:3517160-Antibody-Producing Cells,
pubmed-meshheading:3517160-Exocrine Glands,
pubmed-meshheading:3517160-Fluorescent Antibody Technique,
pubmed-meshheading:3517160-Humans,
pubmed-meshheading:3517160-Immunoglobulin A, Secretory,
pubmed-meshheading:3517160-Intestinal Mucosa,
pubmed-meshheading:3517160-Lymphoid Tissue,
pubmed-meshheading:3517160-Mammary Glands, Animal,
pubmed-meshheading:3517160-Salivary Glands
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pubmed:year |
1986
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pubmed:articleTitle |
Different subclass distribution of IgA-producing cells in human lymphoid organs and various secretory tissues.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|