rdf:type |
|
lifeskim:mentions |
umls-concept:C0002844,
umls-concept:C0014912,
umls-concept:C0015264,
umls-concept:C0025219,
umls-concept:C0033268,
umls-concept:C0034650,
umls-concept:C0034652,
umls-concept:C0036751,
umls-concept:C0038148,
umls-concept:C0039597,
umls-concept:C0039601,
umls-concept:C0681828,
umls-concept:C0851285,
umls-concept:C1280500
|
pubmed:issue |
3
|
pubmed:dateCreated |
1987-3-20
|
pubmed:abstractText |
The possible role of estradiol-17 beta (E2), testosterone (T), 5 alpha-dihydrotestosterone (DHT), melatonin, and serotonin on the regulation of androgen (A) production by the frog, Rana esculenta, testes was studied in vitro. E2 (10(-6) M) inhibited A production whether alone or in combination with oLH (20 micrograms) after 6 hr incubation. After 24 hr incubation. A production was reduced by E2 concentration of around 10(-6) and 10(-9) M. Melatonin and serotonin did not induce any change whichever experimental condition was used. Preincubation for 6 hr with 10(-6) M T or DHT enhanced the oLH-stimulated A production after 18 hr incubation. These data suggest that steroids may regulate their intratesticular levels without passing into the blood stream.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0016-6480
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
64
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
405-10
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3492409-Androgens,
pubmed-meshheading:3492409-Animals,
pubmed-meshheading:3492409-Dihydrotestosterone,
pubmed-meshheading:3492409-Estradiol,
pubmed-meshheading:3492409-Luteinizing Hormone,
pubmed-meshheading:3492409-Male,
pubmed-meshheading:3492409-Melatonin,
pubmed-meshheading:3492409-Rana esculenta,
pubmed-meshheading:3492409-Serotonin,
pubmed-meshheading:3492409-Testis,
pubmed-meshheading:3492409-Testosterone
|
pubmed:year |
1986
|
pubmed:articleTitle |
Regulation of androgen production by frog (Rana esculenta) testis: an in vitro study on the effects exerted by estradiol, 5 alpha-dihydrotestosterone, testosterone, melatonin, and serotonin.
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|