Source:http://linkedlifedata.com/resource/umls/id/C0038148
CSP: potent androgenic metabolite of testosterone; dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone; unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid.,NCI: The most potent androgen, required for sex development. Dihydrotestosterone is synthesized from testosterone in the prostate gland, testes, hair follicles and adrenal glands by 5-alpha reductase. Dihydrotestosterone exerts its action similar to testosterone, which binds to and activates specific nuclear androgen receptors. After translocation into the nucleus, the activated hormone-receptor complex binds to the androgen response elements on the DNA and activates gene expressions that are required for sex development. Dihydrotestosterone is responsible for the formation of male primary sex characteristics and most male secondary sex characteristics during puberty, such as muscular growth, facial and body hair growth, and deepening of the voice.,PDQ: The most potent