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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1978-4-17
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pubmed:abstractText |
In this study 12 patients with mycosis fungoides were treated with whole body topical application of HN2. In addition 4 of these patients had gauzes moistened with the same HN2 solution placed upon plaques and tumours. 4 patients developed in allergic contact dermatitis, and this complication was overcome by percutaneous desensitizing in 3 of them. After starting hydration of plaques and tumours with HN2, the average time to obtain complete clinical remission was shorted from 4.4 to 2.5 months. A little later at the optimal histologic response, there was no or almost no cellular infiltration in 5 cases, while in 6 cases there was only a slight, unspecific, lymphocytic infiltrate in the dermis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0011-9075
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
156
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
129-41
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:342293-Administration, Topical,
pubmed-meshheading:342293-Adult,
pubmed-meshheading:342293-Aged,
pubmed-meshheading:342293-Clinical Trials as Topic,
pubmed-meshheading:342293-Desensitization, Immunologic,
pubmed-meshheading:342293-Drug Evaluation,
pubmed-meshheading:342293-Humans,
pubmed-meshheading:342293-Middle Aged,
pubmed-meshheading:342293-Mycosis Fungoides,
pubmed-meshheading:342293-Nitrogen Mustard Compounds,
pubmed-meshheading:342293-Pigmentation Disorders,
pubmed-meshheading:342293-Remission, Spontaneous,
pubmed-meshheading:342293-Skin Neoplasms
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pubmed:year |
1978
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pubmed:articleTitle |
Remissions of mycosis fungoides induced by nitrogen mustard (HN2). Topical treatment and hydration of tumours and plaques with HN2. Topical desensitization to HN2. A clinical and histopathological controlled study.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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