Linked Life Data

3262695

Source:http://linkedlifedata.com/resource/pubmed/id/3262695

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-11-9
pubmed:abstractText
The purification and initial characterization of a ferret Pneumocystis carinii surface glycoprotein is described. Previous studies have demonstrated that passive administration of monoclonal antibody recognizing this glycoprotein reduces the severity of P. carinii pneumonitis in animal models of infection. This acidic glycoprotein (approximate isoelectric point, 5.0-5.7) contains both mannose (and/or glucose) and N-acetyl-glucosamine residues. The cross-reactive surface antigen on P. carinii of human origin is also a mannose- (and/or glucose-) containing glycoprotein. Initial biochemical characterization of these surface molecules should aid in understanding the immunobiology of this organism and in developing reliable diagnostic assays for P. carinii pneumonitis.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-1899
pubmed:author
pubmed:issnType
Print
pubmed:volume
158
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
848-54
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Purification and initial characterization of a ferret Pneumocystis carinii surface antigen.
pubmed:affiliation
Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't