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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1989-7-18
|
| pubmed:abstractText |
Diazepam and pentobarbital administered intravenously increased food intake in a dose-dependent manner in nondeprived rats. Low doses of naloxone inhibited diazepam-induced feeding, but did not inhibit pentobarbital-induced feeding. On the other hand, picrotoxin inhibited feeding induced by both drugs. These findings suggest that diazepam-induced hyperphagia is related to endogenous opioid mechanisms, but pentobarbital-induced hyperphagia is not. Hyperphagia induced by both drugs may be related to GABAergic neurons.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0091-3057
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
31
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
709-11
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:3251254-Animals,
pubmed-meshheading:3251254-Diazepam,
pubmed-meshheading:3251254-Dose-Response Relationship, Drug,
pubmed-meshheading:3251254-Feeding Behavior,
pubmed-meshheading:3251254-Hyperphagia,
pubmed-meshheading:3251254-Male,
pubmed-meshheading:3251254-Naloxone,
pubmed-meshheading:3251254-Pentobarbital,
pubmed-meshheading:3251254-Picrotoxin,
pubmed-meshheading:3251254-Rats,
pubmed-meshheading:3251254-Rats, Inbred Strains
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Effects of naloxone and picrotoxin on diazepam- or pentobarbital-induced hyperphagia in nondeprived rats.
|
| pubmed:affiliation |
Central Research Laboratories, Banyu Pharmaceutical Co. Ltd., Tokyo, Japan.
|
| pubmed:publicationType |
Journal Article
|