Source:http://linkedlifedata.com/resource/umls/id/C0031890
MSH: A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates.,CSP: nonalkaloid extract from the seeds of Anamirta cocculus used as a CNS and respiratory stimulant to counteract toxicity of CNS depressants such as barbiturates; GABA-A receptor antagonist used to probe GABA function in the CNS.