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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1989-3-17
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pubmed:abstractText |
Chromogranins A and B and secretogranin II have been localized in a wide spectrum of gastroenteropancreatic endocrine/paracrine cells. Chromogranin A immunoreactivity showed the widest distribution and was displayed by glucagon-, PP-, gastrin-, gastrin-CCK-, secretin-immunoreactive cells, the most intense stainings being peculiar of enterochromaffin cells. Chromogranin B immunoreactivity was detected in gastrin- and glucagon cells and in some enterochromaffin cells containing also chromogranin A. Secretogranin II was paired to chromogranin A in glucagon cells of pancreatic islets or occurred alone in glycentin/PP cells of colonic mucosa. Neither of the chromogranins nor secretogranin II have been so far detected in somatostatin-, GIP-, or motilin-immunoreactive cells. Chromogranin A but not chromogranin B or secretogranin II has been detected in the gastric argyrophilic ECL cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0391-7258
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
471-84
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3223865-Animals,
pubmed-meshheading:3223865-Cats,
pubmed-meshheading:3223865-Chromogranin A,
pubmed-meshheading:3223865-Chromogranins,
pubmed-meshheading:3223865-Colon,
pubmed-meshheading:3223865-Digestive System,
pubmed-meshheading:3223865-Dogs,
pubmed-meshheading:3223865-Endocrine Glands,
pubmed-meshheading:3223865-Gastric Mucosa,
pubmed-meshheading:3223865-Guinea Pigs,
pubmed-meshheading:3223865-Immunohistochemistry,
pubmed-meshheading:3223865-Intestinal Mucosa,
pubmed-meshheading:3223865-Intestine, Small,
pubmed-meshheading:3223865-Nerve Tissue Proteins,
pubmed-meshheading:3223865-Pancreas,
pubmed-meshheading:3223865-Proteins,
pubmed-meshheading:3223865-Tissue Distribution
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pubmed:year |
1988
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pubmed:articleTitle |
Chromogranins A and B and secretogranin II in hormonally identified endocrine cells of the gut and the pancreas.
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pubmed:affiliation |
Centro di Diagnostica Istochimica ed Ultrastrutturale, Università di Pavia, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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