Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-3-16
pubmed:abstractText
Tissue concentrations of energetic nucleotides and coenzymes, and oxygen consumption (MO2), have been measured in trout, exposed for 30 min in normoxic conditions (PwO2 congruent to 150 Torr), to 101 ATA (Atmosphere Absolute) of hydrostatic pressure (HP) and compared with results obtained at atmospheric pressure (1 ATA). The results show that in trout exposed to HP, there is an increase in MO2 accompanied by a decrease in ATP and energy charge (EC) in the three tissues explored (brain, liver, and muscle). Moreover, the fall of EC in muscle is accompanied by an increase in inosine 5' monophosphate (IMP). These results are in agreement with the hypothesis of an histotoxic hypoxia induced by HP, which can act at the Krebs cycle level and/or at the respiratory chain level, possibly by uncoupling the respiratory chain from oxidative phosphorylation processes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0176-8638
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
239-42
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Effects of hydrostatic pressure (HP = 101 ATA) on nucleotides and pyridine dinucleotides tissue contents in trout.
pubmed:affiliation
Laboratoire de Physiologie, UA CNRS 648, Faculté de Médecine, France.
pubmed:publicationType
Journal Article