Linked Life Data

3191475

Source:http://linkedlifedata.com/resource/pubmed/id/3191475

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-12-28
pubmed:abstractText
The effect of the tumour-bearing state, with or without induced weight loss on host liver fatty acid synthase and acetyl coenzyme A content has been studied in NMRI mice bearing either the cachexia-inducing colon adenocarcinoma (MAC16) or the related tumour (MAC13), which does not produce weight loss. The specific activity of fatty acid synthase was increased in the host liver of animals bearing either tumour and the hepatic content of acetyl CoA was decreased. Animals bearing the MAC16 tumour fed a diet in which 80% of the calories were supplied as medium chain triglycerides (MCT) had depressed fatty acid synthase and increased acetyl CoA levels, similar to those found in non-tumour-bearing controls.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0304-3835
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
231-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Changes in host liver fatty acid synthase in tumour-bearing mice.
pubmed:affiliation
Pharmaceutical Sciences Institute, Aston University, Birmingham, U.K.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't