Source:http://linkedlifedata.com/resource/umls/id/C0015683
MSH: An enzyme complex of multiple catalytic domains which elongates FATTY ACIDS. The form found in BACTERIA; FUNGI; and PLANTS is different from the form found in ANIMALS. The complex is a target of some ANTINEOPLASTIC AGENTS, some ANTI-OBESITY AGENTS, and some ANTI-INFECTIVE AGENTS.,CSP: animal enzyme is a multi-functional protein catalyzing the reactions of EC 2.3.1.38, EC 2.3.1.39, EC 2.3.1.41, EC 1.1.1.100, EC 4.2.1.61, EC 1.3.1.10, and EC 3.1.2.14.,NCI: Fatty acid synthase (FAS) is a key metabolic enzyme catalyzing the synthesis of long-chain saturated fatty acids. It plays a central role in the production of surfactant in fetal lungs, in the supply of fatty components of milk, and in the conversion and storage of energy in liver and adipose tissue. Remarkably high levels of FAS expression are found in the majority of human epithelial cancers. Experimental manipulation suggests a link between FAS overexpression and dysregulation of membrane composition and functioning in tumor cells. (from Biochem Bioph