Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-12-22
pubmed:abstractText
The present study investigates the effect of a pituitary hormone (luteotrophic hormone, LH) and a thymic factor (thymosin fraction V, TVF) on in vitro and in vivo natural killer (NK) cell activity of BALB/c mice (2, 6 and 8 months old). In vitro it was found that LH at various concentrations (0.5, 5, 50 and 500 ng/ml) significantly reduced the NK cell activity. This inhibition was not blocked by TFV. In vivo it was observed that there was a great inhibition of NK cell activity by LH (5 and 50 ng/ml) on 2- and 6-month-old mice, but a significant increase of NK cell activity on 8-month-old mice. The physiological significance of these observations points to an intimate connection between immune and endocrine system functions.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-2414157, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-3496463, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-3679287, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-376736, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-3890236, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-4399433, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-5823314, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-6272515, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-6381037, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-6606851, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-6693136, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-6775936, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-6821556, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-7025134, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-7027442, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-7056593, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-7101272, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-722074, http://linkedlifedata.com/resource/pubmed/commentcorrection/3181992-957803
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0019-2805
pubmed:author
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
125-8
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Interaction between luteotrophic hormone (LH) and thymosin on natural killer cell activity in BALB/c mice.
pubmed:affiliation
Laboratory of Animal Physiology General and Comparative Immunology, Limoges, France.
pubmed:publicationType
Journal Article