Linked Life Data

3137425

Source:http://linkedlifedata.com/resource/pubmed/id/3137425

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1988-10-7
pubmed:abstractText
Tumor necrosis factor alpha is increasingly being recognized as an important macrophage-derived cytokine that possesses pleomorphic effects in both physiologic and immunologic systems. Current evidence has demonstrated that tumor necrosis factor may stimulate a plethora of cellular responses in vitro and induce multiple physiologic derangements when given in vivo. While the biologic activity of tumor necrosis factor elaborated by macrophages and macrophage cell lines in response to bacterial and protozoal cell products have been well documented, the endogenous factors that regulate the production of this monokine are not as clearly delineated. This chapter focuses on the cellular and molecular mechanisms that endogenously regulate the production of tumor necrosis factor.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0076-681X
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
240-59
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Production and regulation of tumor necrosis factor alpha. A cellular and molecular analysis.
pubmed:affiliation
Department of Pathology, University of Michigan Medical School, Ann Arbor.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't