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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4842
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pubmed:dateCreated |
1988-3-21
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pubmed:abstractText |
In an in vitro system for the Drosophila melanogaster male accessory gland, it was found that 10(-9)M juvenile hormone III could accurately mimic the copulation-induced response of increased protein synthesis in glands from virgin flies. Stimulation by this hormone required calcium in the medium. Experiments with tumor-promoting phorbol esters indicated that activation of protein kinase C can also cause the glands to increase protein synthesis. Stimulation of protein synthesis by juvenile hormone did not occur in mutants deficient in kinase C activity. These results suggest a membrane-protein-mediated effect of juvenile hormone that involves calcium and kinase C.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0036-8075
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
239
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
916-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3124270-Animals,
pubmed-meshheading:3124270-Calcium,
pubmed-meshheading:3124270-Drosophila melanogaster,
pubmed-meshheading:3124270-Enzyme Activation,
pubmed-meshheading:3124270-Genitalia, Male,
pubmed-meshheading:3124270-Juvenile Hormones,
pubmed-meshheading:3124270-Male,
pubmed-meshheading:3124270-Membrane Proteins,
pubmed-meshheading:3124270-Mutation,
pubmed-meshheading:3124270-Phorbol 12,13-Dibutyrate,
pubmed-meshheading:3124270-Phorbol Esters,
pubmed-meshheading:3124270-Protein Biosynthesis,
pubmed-meshheading:3124270-Protein Kinase C,
pubmed-meshheading:3124270-Sesquiterpenes,
pubmed-meshheading:3124270-Tetradecanoylphorbol Acetate
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pubmed:year |
1988
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pubmed:articleTitle |
Juvenile hormone action mediated in male accessory glands of Drosophila by calcium and kinase C.
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pubmed:affiliation |
Molecular Biology Section, University of Southern California, Los Angeles 90089.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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