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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1988-9-26
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pubmed:abstractText |
Since granulocyte/macrophage colony-stimulating factor (GM-CSF) has been reported to stimulate the proliferation of clonogenic leukemia cells from patients with acute non-lymphocytic leukemia in vitro, the expression of the GM-CSF gene in primary human leukemic blast cells was studied. T-cell-depleted mononuclear cells in freshly drawn peripheral blood from patients with acute non-lymphocytic leukemia (ANLL) were subjected to the study. The expression of the GM-CSF gene was detected by Northern blotting analysis using [32P]GM-CSF as a probe. The GM-CSF gene was expressed in two out of five cases examined. In both of the patients who showed GM-CSF expression, remission could not be achieved.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0753-3322
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
65-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3044458-Acute Disease,
pubmed-meshheading:3044458-Colony-Stimulating Factors,
pubmed-meshheading:3044458-Genes,
pubmed-meshheading:3044458-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:3044458-Granulocytes,
pubmed-meshheading:3044458-Growth Substances,
pubmed-meshheading:3044458-Humans,
pubmed-meshheading:3044458-Leukemia,
pubmed-meshheading:3044458-Macrophages,
pubmed-meshheading:3044458-RNA, Messenger
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pubmed:year |
1988
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pubmed:articleTitle |
Expression of the granulocyte/macrophage colony-stimulating factor gene in leukemic blast cells from patients with acute non-lymphocytic leukemia.
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pubmed:affiliation |
Cancer Center, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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