Linked Life Data

3026399

Source:http://linkedlifedata.com/resource/pubmed/id/3026399

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1987-2-10
pubmed:abstractText
Polyadenylation of mRNA, a post-transcriptional phenomenon, is catalysed by cytoplasmic and nuclear poly(A) polymerases. During normal growth and development cytoplasmic poly(A) polymerase activity in the kidney of rat increased from day 20 reaching to a peak at 35 days. Dihydrotestosterone at a dose of 500 micrograms and above significantly stimulated the enzyme activity in the cortex of kidney in the castrated animals. A single dose of dihydrotestosterone caused significant increase in the enzyme activity at 12 h after treatment and was maintained till 24 h. Antiandrogen cyproterone acetate inhibited dihydrotestosterone-induced enzyme activity in kidney cortex. These results show that cytoplasmic poly(A) polymerase of rat kidney is regulated by dihydrotestosterone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0158-5231
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1037-44
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Regulation of cytoplasmic poly(A) polymerase activity by dihydrotestosterone in the kidney of rat.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't