|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0012906,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0033488,
umls-concept:C0035681,
umls-concept:C0449432,
umls-concept:C0521009,
umls-concept:C1179435,
umls-concept:C1524073,
umls-concept:C1548799,
umls-concept:C1705248
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|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1986-8-14
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|
pubmed:abstractText |
Several UV-absorbing substances inhibiting the DNA-dependent RNA polymerases of Escherichia coli and Streptomyces aureofaciens, as well as the restriction endonuclease Eco RI have been isolated from the water-soluble extract of Propolis by two-dimensional paper chromatography. The inhibition of bacterial RNA-polymerases by the components of Propolis was probably due to the loss of their ability to bind to DNA. The general characteristic of the UV-absorbing component of Propolis with the most pronounced inhibitory effect upon transcription in vitro is described.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Feb
|
|
pubmed:issn |
0031-7144
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
41
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
131-2
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pubmed:dateRevised |
2007-1-29
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pubmed:meshHeading |
pubmed-meshheading:3014571-Chromatography, Paper,
pubmed-meshheading:3014571-DNA, Viral,
pubmed-meshheading:3014571-DNA Restriction Enzymes,
pubmed-meshheading:3014571-DNA-Directed RNA Polymerases,
pubmed-meshheading:3014571-Deoxyribonuclease I,
pubmed-meshheading:3014571-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:3014571-Escherichia coli,
pubmed-meshheading:3014571-Pancreas,
pubmed-meshheading:3014571-Propolis,
pubmed-meshheading:3014571-Resins, Plant,
pubmed-meshheading:3014571-Spectrophotometry, Ultraviolet,
pubmed-meshheading:3014571-Transcription, Genetic
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|
pubmed:year |
1986
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pubmed:articleTitle |
Inhibition of bacterial DNA-dependent RNA polymerases and restriction endonuclease by UV-absorbing components from propolis.
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pubmed:publicationType |
Journal Article
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