Source:http://linkedlifedata.com/resource/umls/id/C0035681
MSH: Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).,NCI: RNA polymerases comprise a group of enzymes that catalyze extension, one nucleotide at a time, of the 3 prime-end of an RNA strand along a complementary DNA template.,NCI: An enzyme that catalyzes the stepwise addition of ribonucleotides to the 3' end of a growing RNA chain using a single-stranded DNA template. This reaction, transcription, is important in the flow of information from DNA to proteins. Three different polymerase protein complexes have been identified and characterized.