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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1986-3-28
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pubmed:abstractText |
Transfection of Epstein-Barr virus (EBV)-nonproducer Raji cells with the BamHI Z fragment of EBV DNA induced antigens that were detected with human antiserum against EBV-specific early antigens. Northern blot analysis of transfected cells revealed that one intense RNA band hybridized with the BamHI H and F fragments but not with the BamHI Z fragment. Cooperation between the BamHI H, F, and BamHI Z regions was also confirmed in baby hamster kidney cells that were cotransfected with both fragments. These results indicate that the transfected BamHI Z fragment of EBV DNA induces a trans-acting factor which activates the gene expression of the BamHI H and F region and that the BamHI Z region possibly plays an important role in the latency of EBV.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-1055375,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-14304234,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-204874,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-210957,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-213727,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-220786,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-2982034,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-2982497,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-2987963,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-4133943,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-4160230,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-4306521,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-4316788,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-4346033,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-4501582,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-4504350,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-4550511,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-4550512,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-4710584,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-4878906,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-4912237,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6087149,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6159641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6248879,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6249024,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6262773,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6268847,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6270894,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6310587,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6313969,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6319296,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6322426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6323326,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6325929,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-6328012,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-7071022,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-881736,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3005608-922889
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1016-22
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3005608-Animals,
pubmed-meshheading:3005608-Antigens, Viral,
pubmed-meshheading:3005608-Cricetinae,
pubmed-meshheading:3005608-DNA, Viral,
pubmed-meshheading:3005608-Genes, Viral,
pubmed-meshheading:3005608-Genetic Vectors,
pubmed-meshheading:3005608-Herpesvirus 4, Human,
pubmed-meshheading:3005608-Humans,
pubmed-meshheading:3005608-Plasmids,
pubmed-meshheading:3005608-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:3005608-Transcription, Genetic,
pubmed-meshheading:3005608-Transfection
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pubmed:year |
1986
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pubmed:articleTitle |
trans activation of the latent Epstein-Barr virus (EBV) genome after transfection of the EBV DNA fragment.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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