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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1986-2-20
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pubmed:abstractText |
Human subjects submitted to treatment with morphine show a severe depression of phagocytosis, killing properties and superoxide production both of their polymorphonuclear leukocytes and monocytes. Polymorphonuclear leukocyte adherence, chemotaxis, random migration, myeloperoxidase content, lysozyme content and lymphocyte Rosette E formation were poorly influenced. Methadone-treated subjects show a similar effect at phagocytic level but far less evident. These results confirm those previously found in animals and reinforce the evidence of a depressive role of morphine on phagocytic physiology.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0192-0561
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
7
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
865-74
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3000961-Cytotoxicity, Immunologic,
pubmed-meshheading:3000961-Humans,
pubmed-meshheading:3000961-Immunosuppressive Agents,
pubmed-meshheading:3000961-Methadone,
pubmed-meshheading:3000961-Monocytes,
pubmed-meshheading:3000961-Morphine Dependence,
pubmed-meshheading:3000961-Neutrophils,
pubmed-meshheading:3000961-Phagocytes,
pubmed-meshheading:3000961-Phagocytosis,
pubmed-meshheading:3000961-Superoxides
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pubmed:year |
1985
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pubmed:articleTitle |
Morphine and methadone impact on human phagocytic physiology.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|