Linked Life Data

2974909

Source:http://linkedlifedata.com/resource/pubmed/id/2974909

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
23
pubmed:dateCreated
1989-2-23
pubmed:abstractText
In 11 patients with acute myocardial infarction (mean age 52 +/- 6 years) coronary angiography was performed 4.5 +/- 3.6 h after the onset of symptoms. The infarct-related artery was in 7 cases the right coronary artery and in 4 cases the left anterior descending branch of the left coronary artery. The infarct-related artery showed total or subtotal occlusion and no perfusion (Thrombolysis in Myocardial Infarction trial (TIMI) grade 0 or 1). In 7 cases Urokinase was infused intracoronarily at a dosage of 250,000 IU over 30 min, but in only 1 case partial reperfusion was achieved. However, all patients treated with 500,000 IU Urokinase over 30 min or 1 Mill IU over 60 min had successful reperfusion (TIMI grade 2 or 3). Thus, it appears that 500,000 IU up to 1 Mill IU of Urokinase over a period of 30 to 60 min is adequate for intracoronary thrombolysis in patients with acute myocardial infarction.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0023-2173
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1193-5
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
[The dose of intracoronary urokinase infusion in acute myocardial infarct].
pubmed:affiliation
Abteilung Kardiologie und Pulmonologie, Universität Göttingen.
pubmed:publicationType
Journal Article, English Abstract, Case Reports