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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1986-7-16
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pubmed:abstractText |
Following 20 weeks of treatment with isotretinoin, sebaceous glands in patients with cystic acne shrank in size. The cells remaining in the sebaceous lobules were mainly mature lipid-filled cells, with some undifferentiated cells still present at the periphery. The ultrastructure of the glands 8 weeks after cessation of treatment was directly related to the drug dose given each patient. The larger the dose, the slower the return to pretreatment morphology. In those patients given a lower dose, most of the glands observed 2 months after treatment was stopped were similar in size to those seen prior to treatment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0193-1091
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
139-43
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2940935-Acne Vulgaris,
pubmed-meshheading:2940935-Cell Differentiation,
pubmed-meshheading:2940935-Cysts,
pubmed-meshheading:2940935-Dose-Response Relationship, Drug,
pubmed-meshheading:2940935-Humans,
pubmed-meshheading:2940935-Isotretinoin,
pubmed-meshheading:2940935-Sebaceous Glands,
pubmed-meshheading:2940935-Tretinoin
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pubmed:year |
1986
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pubmed:articleTitle |
Ultrastructural changes in sebaceous glands following treatment of cystic acne with isotretinoin.
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pubmed:publicationType |
Journal Article
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