Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1989-4-17
pubmed:abstractText
Brain imaging studies may help to localize areas particularly sensitive to cholinergic agonists. A study in rats using the 2-deoxyglucose method for studying changes in brain metabolic activity was performed. Among regions in the pons/medulla, arecoline, 0.05 mg/kg ip, increased glucose utilization in the dorsal raphe, median raphe, and basilar pontine nuclei without producing behavioral or cardiovascular effects. These brain areas, along with the hippocampus, may be pertinent to studies of muscarinic supersensitivity in humans.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0006-3223
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
618-25
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Measuring cholinergic sensitivity: II. Arecoline effects on metabolic activity in pontine regions of rat brain.
pubmed:affiliation
Laboratory of Neurosciences, National Institute on Aging, Bethesda, MD.
pubmed:publicationType
Journal Article