|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001159,
umls-concept:C0026820,
umls-concept:C0037473,
umls-concept:C0040300,
umls-concept:C0042360,
umls-concept:C0205263,
umls-concept:C0279023,
umls-concept:C0442805,
umls-concept:C0456205,
umls-concept:C0871261,
umls-concept:C0999699,
umls-concept:C1550605,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1987-6-26
|
|
pubmed:abstractText |
Aconitine potentiated the contractile response of the guinea-pig vas deferens and increased the tissue Na and Ca content. These effects were abolished in the presence of tetrodotoxin. These results suggest that aconitine causes an increasing Na+ permeability of the smooth muscle membrane to increase Ca2+ availability and thus induces potentiation.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0022-3573
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
39
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
324-6
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:2884304-Aconitine,
pubmed-meshheading:2884304-Aconitum,
pubmed-meshheading:2884304-Animals,
pubmed-meshheading:2884304-Calcium,
pubmed-meshheading:2884304-Cricetinae,
pubmed-meshheading:2884304-Male,
pubmed-meshheading:2884304-Muscle, Smooth,
pubmed-meshheading:2884304-Muscle Contraction,
pubmed-meshheading:2884304-Norepinephrine,
pubmed-meshheading:2884304-Sodium,
pubmed-meshheading:2884304-Tetrodotoxin,
pubmed-meshheading:2884304-Vas Deferens
|
|
pubmed:year |
1987
|
|
pubmed:articleTitle |
Potentiation of contractile response and increase in tissue sodium content induced by aconitine in the guinea-pig vas deferens.
|
|
pubmed:publicationType |
Journal Article,
In Vitro
|
