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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1988-10-13
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pubmed:abstractText |
An inhibitor of collagenase was released from cultured cervical tissue of sheep and the amounts released were greatest from tissue in late pregnancy (145-146 days). The molecular weights of material with inhibitory activity, estimated by gel filtration of extracted inhibitor, at different stages of pregnancy were different, i.e. 20,000 from extracts of late-pregnant and post-partum samples and 29,000 from extracts of non-pregnant samples. Inhibitor from culture supernatants had a molecular weight of 42,000. We conclude that the inhibitor has binding characteristics and molecular weights similar to those of the tissue inhibitor of metalloproteinase.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-4251
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
83
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
893-900
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pubmed:dateRevised |
2010-8-25
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pubmed:meshHeading |
pubmed-meshheading:2842500-Animals,
pubmed-meshheading:2842500-Cervix Uteri,
pubmed-meshheading:2842500-Culture Techniques,
pubmed-meshheading:2842500-Female,
pubmed-meshheading:2842500-Labor, Obstetric,
pubmed-meshheading:2842500-Microbial Collagenase,
pubmed-meshheading:2842500-Molecular Weight,
pubmed-meshheading:2842500-Pregnancy,
pubmed-meshheading:2842500-Sheep
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pubmed:year |
1988
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pubmed:articleTitle |
Collagenase inhibitor concentration in cultured cervical tissue of sheep is increased in late pregnancy.
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pubmed:affiliation |
Department of Biochemistry and Molecular Biology, Manchester University, U.K.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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