Linked Life Data

2824534

Source:http://linkedlifedata.com/resource/pubmed/id/2824534

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1988-1-21
pubmed:abstractText
Until about two years ago, the only known function of tumor necrosis factor (TNF) was inhibition of tumor growth. Since then it has become apparent that many types of normal and transformed cells express specific high-affinity TNF receptors (Kd 200 pM) and that the presence of receptors does not correlate with susceptibility to the cytotoxic/cytostatic action of TNF. Recent evidence shows that TNF exerts a variety of other important biological activities on cells in culture and in the intact organism. Among the newly recognized activities is a potent mitogenic effect in fibroblasts. Many of the activities of TNF overlap the actions of interleukin-1 (IL-1).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0737-1462
pubmed:author
pubmed:issnType
Print
pubmed:volume
Suppl 5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-61
pubmed:dateRevised
2008-2-12
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Tumor necrosis factor: receptor binding and mitogenic action in fibroblasts.
pubmed:affiliation
Department of Microbiology, New York University Medical Center, NY 10016.
pubmed:publicationType
Journal Article, Comparative Study, Review