Linked Life Data

2802626

Source:http://linkedlifedata.com/resource/pubmed/id/2802626

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-11-3
pubmed:abstractText
Lycopene, a biologically occurring carotenoid, exhibits the highest physical quenching rate constant with singlet oxygen (kq = 31 X 10(9) M-1 s-1), and its plasma level is slightly higher than that of beta-carotene (kq = 14 X 10(9) M-1 s-1). This is of considerable general interest, since nutritional carotenoids, particularly beta-carotene, and other antioxidants such as alpha-tocopherol (kq = 0.3 X 10(9) M-1 s-1) have been implicated in the defense against prooxidant states; epidemiological evidence reveals that such compounds exert a protective action against certain types of cancer. Also, albumin-bound bilirubin is a known singlet oxygen quencher (kq = 3.2 X 10(9) M-1 s-1). Interestingly, those compounds with low kq values occur at higher plasma levels. When these differences are taken into account, the singlet oxygen quenching capacities of lycopene (0.7 microM in plasma), beta-carotene (0.5 microM in plasma), albumin-bound bilirubin (15 microM in plasma), and alpha-tocopherol (22 microM in plasma) are of comparable magnitude.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0003-9861
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
274
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
532-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Lycopene as the most efficient biological carotenoid singlet oxygen quencher.
pubmed:affiliation
Institut für Physiologische Chemie I, Universität Düsseldorf, Federal Republic of Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't