| pubmed-article:2754359 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2754359 | lifeskim:mentions | umls-concept:C0040300 | lld:lifeskim |
| pubmed-article:2754359 | lifeskim:mentions | umls-concept:C0007452 | lld:lifeskim |
| pubmed-article:2754359 | lifeskim:mentions | umls-concept:C0929301 | lld:lifeskim |
| pubmed-article:2754359 | lifeskim:mentions | umls-concept:C0006141 | lld:lifeskim |
| pubmed-article:2754359 | lifeskim:mentions | umls-concept:C0037663 | lld:lifeskim |
| pubmed-article:2754359 | lifeskim:mentions | umls-concept:C0021965 | lld:lifeskim |
| pubmed-article:2754359 | lifeskim:mentions | umls-concept:C0169964 | lld:lifeskim |
| pubmed-article:2754359 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:2754359 | lifeskim:mentions | umls-concept:C2828358 | lld:lifeskim |
| pubmed-article:2754359 | lifeskim:mentions | umls-concept:C0442805 | lld:lifeskim |
| pubmed-article:2754359 | lifeskim:mentions | umls-concept:C0202056 | lld:lifeskim |
| pubmed-article:2754359 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2754359 | pubmed:dateCreated | 1989-8-30 | lld:pubmed |
| pubmed-article:2754359 | pubmed:abstractText | The effect of administration of bovine somatotrophin (bST) on peripheral conversion of thyroxine (T4) to tri-iodothyronine (T3) was studied in non-pregnant lactating Holstein cows. Six cows were injected daily for 5 days with 40 mg recombinantly derived bST, while six control cows received excipient alone. Blood samples were collected hourly from 08.00 to 19.00 h on a single day the week before treatment and on days 4-5 of treatment. All other tissue samples were obtained at slaughter, 20-23 h after the last injection. Administration of bST increased milk production and caused a 9% increase in hepatic DNA. Consumption of feed did not differ between control and bST-treated cows. Treatment did not alter serum concentrations of T4 or T3, although concentrations of thyroid hormones in the serum increased from 08.00 to 19.00 h. Activity of thyroxine-5'-monodeiodinase (5'-D) in liver and kidney was similarly unaffected. However, activity of 5'-D in mammary tissue increased approximately twofold in response to bST administration. We suggest that an increase in mammary conversion of T4 to the more biologically potent thyroid hormone T3 plays a role in mediating the galactopoietic response of dairy cattle to bST. | lld:pubmed |
| pubmed-article:2754359 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2754359 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2754359 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2754359 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2754359 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2754359 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2754359 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2754359 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2754359 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2754359 | pubmed:month | May | lld:pubmed |
| pubmed-article:2754359 | pubmed:issn | 0022-0795 | lld:pubmed |
| pubmed-article:2754359 | pubmed:author | pubmed-author:SmithJ JJJ | lld:pubmed |
| pubmed-article:2754359 | pubmed:author | pubmed-author:KeysJ EJE | lld:pubmed |
| pubmed-article:2754359 | pubmed:author | pubmed-author:CapucoA VAV | lld:pubmed |
| pubmed-article:2754359 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2754359 | pubmed:volume | 121 | lld:pubmed |
| pubmed-article:2754359 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2754359 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2754359 | pubmed:pagination | 205-11 | lld:pubmed |
| pubmed-article:2754359 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:2754359 | pubmed:meshHeading | pubmed-meshheading:2754359-... | lld:pubmed |
| pubmed-article:2754359 | pubmed:meshHeading | pubmed-meshheading:2754359-... | lld:pubmed |
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| pubmed-article:2754359 | pubmed:meshHeading | pubmed-meshheading:2754359-... | lld:pubmed |
| pubmed-article:2754359 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2754359 | pubmed:articleTitle | Somatotrophin increases thyroxine-5'-monodeiodinase activity in lactating mammary tissue of the cow. | lld:pubmed |
| pubmed-article:2754359 | pubmed:affiliation | Milk Secretion and Mastitis Laboratory, USDA, Beltsville, Maryland 20705. | lld:pubmed |
| pubmed-article:2754359 | pubmed:publicationType | Journal Article | lld:pubmed |
