Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1989-8-25
|
pubmed:abstractText |
An immunohistochemical method (peroxidase antiperoxidase method) was carried out to examine the distribution of endogenous estradiol (E2) and testosterone (Te). One hundred and twenty four (48.2%) of 257 colo-rectal cancer cases, and 36.7% of male cases and 58.4% of female cases revealed E2-immunostain. This immunohistochemical reaction for E2 was found more frequently in female patients than in male patients, while Te-immunostain was found in 15 (17.6%) of 85 colo-rectal cancer cases. E2 and Te were demonstrated mainly in the cytoplasms and occasionally in the nuclei of cancer cells. Since E2 or Te-positive cancer cells were mainly distributed in the deeper or invasive portion of tissue sections, it might deserve further investigation to elucidate a certain relationship between cancer growth and endogenous sex-hormones.
|
pubmed:language |
jpn
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0446-6586
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
86
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
200-7
|
pubmed:dateRevised |
2011-8-2
|
pubmed:meshHeading |
pubmed-meshheading:2666696-Colorectal Neoplasms,
pubmed-meshheading:2666696-Cytoplasm,
pubmed-meshheading:2666696-Estradiol,
pubmed-meshheading:2666696-Female,
pubmed-meshheading:2666696-Humans,
pubmed-meshheading:2666696-Immunoenzyme Techniques,
pubmed-meshheading:2666696-Male,
pubmed-meshheading:2666696-Neoplasm Invasiveness,
pubmed-meshheading:2666696-Sex Factors,
pubmed-meshheading:2666696-Testosterone
|
pubmed:year |
1989
|
pubmed:articleTitle |
[An immunohistochemical study of endogenous estradiol and testosterone in human colo-rectal cancer tissues].
|
pubmed:publicationType |
Journal Article,
English Abstract
|