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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1989-6-27
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pubmed:abstractText |
The endogenous opioid system plays an important role in the control of feeding behavior. Previous research has shown that antagonism of endogenous opioids will suppress feeding in certain models in both human and infrahuman species. In the current study, 16 normal-weight bulimic women were treated with low-dose naltrexone, the long-acting, orally active narcotic antagonist, and placebo in a crossover design. The use of the active drug was not associated with a clinically significant reduction in binge eating or vomiting episodes. Suggestions for further research in this area are offered.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0271-0749
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
94-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2656781-Adult,
pubmed-meshheading:2656781-Bulimia,
pubmed-meshheading:2656781-Clinical Trials as Topic,
pubmed-meshheading:2656781-Double-Blind Method,
pubmed-meshheading:2656781-Female,
pubmed-meshheading:2656781-Humans,
pubmed-meshheading:2656781-Naltrexone,
pubmed-meshheading:2656781-Psychiatric Status Rating Scales,
pubmed-meshheading:2656781-Random Allocation
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pubmed:year |
1989
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pubmed:articleTitle |
A placebo-controlled, double-blind crossover study of naltrexone hydrochloride in outpatients with normal weight bulimia.
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pubmed:affiliation |
Department of Psychiatry, University of Minnesota Medical School, Minneapolis 55455.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't
|