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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
1989-5-24
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pubmed:databankReference |
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pubmed:abstractText |
Using low-stringency hybridization to the rat brain glucose transporter (GT), a 2489-base-pair cDNA clone was isolated from a rat soleus lambda gt10 cDNA library. It encodes a 509-amino acid protein whose sequence and predicted membrane structure is very similar to those of the rat brain and liver GTs. The muscle GT-like protein is 65% identical in amino acid sequence to the rat brain GT and 52% identical to the rat liver GT; the major differences are in the NH2- and COOH-terminal hydrophilic segments. This GT-like mRNA is expressed predominately in tissues where glucose transport is sensitive to insulin, including striated muscle, cardiac muscle, and adipose tissue; low-level expression is also detected in smooth muscle and kidney mRNA. This GT-like cDNA is the fourth member of the mammalian GT-related gene family identified to date. We propose that it encodes an insulin-sensitive GT.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-1195397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-2410404,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-2418735,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-2440339,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-2446136,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-271968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-2957373,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3016720,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3027132,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3045114,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3047124,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3047589,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3048704,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3058203,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3060567,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3137219,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3158511,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3170580,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3276714,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3281163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3285221,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3301853,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3316205,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3335504,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3399500,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3533934,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3536924,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3536929,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3539932,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3543693,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3546294,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3839598,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3882703,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3888079,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-3915254,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-6091052,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-6159641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-6312838,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-6546423,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-6575390,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-6771756,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-7014557,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-7108955,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-7196262,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2649883-911786
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2535-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:2649883-Amino Acid Sequence,
pubmed-meshheading:2649883-Animals,
pubmed-meshheading:2649883-Base Sequence,
pubmed-meshheading:2649883-Cloning, Molecular,
pubmed-meshheading:2649883-DNA,
pubmed-meshheading:2649883-Insulin,
pubmed-meshheading:2649883-Molecular Sequence Data,
pubmed-meshheading:2649883-Monosaccharide Transport Proteins,
pubmed-meshheading:2649883-Multigene Family,
pubmed-meshheading:2649883-Muscles,
pubmed-meshheading:2649883-Rats,
pubmed-meshheading:2649883-Tissue Distribution
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pubmed:year |
1989
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pubmed:articleTitle |
A glucose transport protein expressed predominately in insulin-responsive tissues.
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pubmed:affiliation |
Whitehead Institute for Biomedical Research, Cambridge, MA 02142.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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