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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1985-6-10
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pubmed:abstractText |
Specific antiphosphorylcholine immune responses were found to be elicited by different Neisseria meningitidis group B M986 preparations. Our results suggest the functional presence of phosphorylcholine in the bacteria. The immune responses, mostly immunoglobulin M, were measured with a plaque-forming cell assay. The secondary phosphorylcholine-specific immune response induced by intact meningococci was significantly lower than the primary phosphorylcholine-specific immune response induced by the same antigens. This suppression is priming time dependent and does not represent an early switching to the expression of other classes of immunoglobulins.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-109572,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-1260526,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-13957684,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-354797,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-43667,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-4964859,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-5059886,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-5653817,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6131872,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6187586,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6409879,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6416146,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6417015,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6417025,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6420031,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6424916,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6424917,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6600188,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6768797,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6806385,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6818147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-6966310,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-7023954,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-7035186,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-7041944,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-7300686,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-78894,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-810478,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-821921,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-825573,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2580791-88491
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
428-32
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2580791-Animals,
pubmed-meshheading:2580791-Antibodies, Bacterial,
pubmed-meshheading:2580791-Choline,
pubmed-meshheading:2580791-Epitopes,
pubmed-meshheading:2580791-Female,
pubmed-meshheading:2580791-Immunization,
pubmed-meshheading:2580791-Immunoglobulin A,
pubmed-meshheading:2580791-Immunoglobulin G,
pubmed-meshheading:2580791-Immunoglobulin M,
pubmed-meshheading:2580791-Immunologic Memory,
pubmed-meshheading:2580791-Male,
pubmed-meshheading:2580791-Mice,
pubmed-meshheading:2580791-Mice, Inbred BALB C,
pubmed-meshheading:2580791-Mice, Inbred CBA,
pubmed-meshheading:2580791-Neisseria meningitidis,
pubmed-meshheading:2580791-Phosphorylcholine,
pubmed-meshheading:2580791-Polysaccharides, Bacterial
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pubmed:year |
1985
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pubmed:articleTitle |
Immunoresponses to Neisseria meningitidis epitopes: primary versus secondary antiphosphorylcholine responses.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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