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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1989-8-30
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pubmed:abstractText |
The in vivo dose-response potential of recombinant human granulocyte colony-stimulating factor (rG-CSF) in facilitating reconstitution of granulopoiesis was evaluated in an 11-year-old girl who received autotransplantation of peripheral blood stem cells (PBSC) after marrow-ablative therapy for relapsing acute lymphoblastic leukemia. The recovery of hematopoiesis was slow when a small number of progenitors were collected and reinfused into the patient, but administration of rG-CSF led to significant dose-dependent increase in peripheral blood granulocytes.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0001-5792
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
81
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
210-2
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2474229-Blood Transfusion, Autologous,
pubmed-meshheading:2474229-Child,
pubmed-meshheading:2474229-Colony-Stimulating Factors,
pubmed-meshheading:2474229-Combined Modality Therapy,
pubmed-meshheading:2474229-Dose-Response Relationship, Drug,
pubmed-meshheading:2474229-Female,
pubmed-meshheading:2474229-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:2474229-Granulocytes,
pubmed-meshheading:2474229-Hematopoiesis,
pubmed-meshheading:2474229-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:2474229-Humans,
pubmed-meshheading:2474229-Leukocyte Count,
pubmed-meshheading:2474229-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:2474229-Recombinant Proteins
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pubmed:year |
1989
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pubmed:articleTitle |
In vivo dose-response effect of recombinant human granulocyte colony-stimulating factor on increase in granulocytes after peripheral blood stem cell autotransplantation.
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pubmed:affiliation |
Department of Pediatrics, University of Tokushima, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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