pubmed-article:2468648 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2468648 | lifeskim:mentions | umls-concept:C0162570 | lld:lifeskim |
pubmed-article:2468648 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
pubmed-article:2468648 | lifeskim:mentions | umls-concept:C0374711 | lld:lifeskim |
pubmed-article:2468648 | lifeskim:mentions | umls-concept:C0043240 | lld:lifeskim |
pubmed-article:2468648 | lifeskim:mentions | umls-concept:C0034286 | lld:lifeskim |
pubmed-article:2468648 | lifeskim:mentions | umls-concept:C0057460 | lld:lifeskim |
pubmed-article:2468648 | lifeskim:mentions | umls-concept:C0059945 | lld:lifeskim |
pubmed-article:2468648 | lifeskim:mentions | umls-concept:C1705181 | lld:lifeskim |
pubmed-article:2468648 | lifeskim:mentions | umls-concept:C1548602 | lld:lifeskim |
pubmed-article:2468648 | lifeskim:mentions | umls-concept:C0163877 | lld:lifeskim |
pubmed-article:2468648 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:2468648 | pubmed:dateCreated | 1989-6-7 | lld:pubmed |
pubmed-article:2468648 | pubmed:abstractText | The role of exonuclease III and endonuclease IV in the repair of pyrimidine dimers in bacteriophage T4-infected Escherichia coli was examined. UV-irradiated T4 showed reduced survival when plated on an xth nfo double mutant but showed wild-type survival on either single mutant. T4 denV phage were equally sensitive when plated on wild-type E. coli or an xth nfo double mutant, suggesting that these endonucleases function in the same repair pathway as T4 pyrimidine dimer-DNA glycosylase. A uvrA mutant of E. coli in which the repair of pyrimidine dimers was dependent on the T4 denV gene carried on a plasmid was constructed. Neither an xth nor an nfo derivative of this strain was more sensitive than the parental strain to UV irradiation. We were unable to construct a uvrA xth nfo triple mutant. In addition, T4, which turns off the host UvrABC excision nuclease, showed reduced plating efficiency on an xth nfo double mutant. | lld:pubmed |
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pubmed-article:2468648 | pubmed:language | eng | lld:pubmed |
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pubmed-article:2468648 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:2468648 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2468648 | pubmed:month | May | lld:pubmed |
pubmed-article:2468648 | pubmed:issn | 0021-9193 | lld:pubmed |
pubmed-article:2468648 | pubmed:author | pubmed-author:CunninghamR... | lld:pubmed |
pubmed-article:2468648 | pubmed:author | pubmed-author:SaporitoS MSM | lld:pubmed |
pubmed-article:2468648 | pubmed:author | pubmed-author:GedenkMM | lld:pubmed |
pubmed-article:2468648 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2468648 | pubmed:volume | 171 | lld:pubmed |
pubmed-article:2468648 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2468648 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2468648 | pubmed:pagination | 2542-6 | lld:pubmed |
pubmed-article:2468648 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:2468648 | pubmed:year | 1989 | lld:pubmed |
pubmed-article:2468648 | pubmed:articleTitle | Role of exonuclease III and endonuclease IV in repair of pyrimidine dimers initiated by bacteriophage T4 pyrimidine dimer-DNA glycosylase. | lld:pubmed |
pubmed-article:2468648 | pubmed:affiliation | Department of Biological Sciences, State University of New York, Albany 12222. | lld:pubmed |
pubmed-article:2468648 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2468648 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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